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Human Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death that often goes undetected in the general population. HCM is also prevalent in patients with cardio-facio-cutaneous syndrome (CFCS), which is a genetic disorder characterized by aberrant signaling in the RAS/MAPK signaling...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Cashman, Timothy J., Josowitz, Rebecca, Johnson, Bryce V., Gelb, Bruce D., Costa, Kevin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718533/
https://ncbi.nlm.nih.gov/pubmed/26784941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146697
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