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Oral Administration of Silkworm-Produced GAD65 and Insulin Bi-Autoantigens against Type 1 Diabetes

Induction of mucosal tolerance by oral administration of protein antigens is a potential therapeutic strategy for preventing and treating type 1 diabetes (T1D); however, the requirement for a large dosage of protein limits clinical applications because of the low efficacy. In this study, we generate...

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Publicat a:PLoS One
Autors principals: Liu, Baoping, Yue, Yuan, Yang, Yun, Jin, Yongfeng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718521/
https://ncbi.nlm.nih.gov/pubmed/26783749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147260
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