Загрузка...
p97/VCP promotes Cullin‐RING‐ubiquitin‐ligase/proteasome‐dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα
Cullin‐RING‐ubiquitin‐ligase (CRL)‐dependent ubiquitination of the nuclear factor kappa B (NF‐κB) inhibitor IκBα and its subsequent degradation by the proteasome usually precede NF‐κB/RelA nuclear activity. Through removal of the CRL‐activating modification of their cullin subunit with the ubiquitin...
Сохранить в:
| Опубликовано в: : | J Cell Mol Med |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717852/ https://ncbi.nlm.nih.gov/pubmed/26463447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12702 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|