Global translational impacts of the loss of the tRNA modification t(6)A in yeast

The universal tRNA modification t(6)A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t(6)A(37) leads to severe growth defects in baker’s yeast, phenotypes similar to those caused by defects in mcm(5)s(2)U(34) synthesis. Mutants in mcm(5)s(2)U(34) can be suppressed by...

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Опубликовано в: :Microb Cell
Главные авторы: Thiaville, Patrick C., Legendre, Rachel, Rojas-Benítez, Diego, Baudin-Baillieu, Agnès, Hatin, Isabelle, Chalancon, Guilhem, Glavic, Alvaro, Namy, Olivier, de Crécy-Lagard, Valérie
Формат: Artigo
Язык:Inglês
Опубликовано: Shared Science Publishers OG 2015
Предметы:
Microbiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717488/
https://ncbi.nlm.nih.gov/pubmed/26798630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2016.01.473
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