Global translational impacts of the loss of the tRNA modification t(6)A in yeast

The universal tRNA modification t(6)A is found at position 37 of nearly all tRNAs decoding ANN codons. The absence of t(6)A(37) leads to severe growth defects in baker’s yeast, phenotypes similar to those caused by defects in mcm(5)s(2)U(34) synthesis. Mutants in mcm(5)s(2)U(34) can be suppressed by...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Thiaville, Patrick C., Legendre, Rachel, Rojas-Benítez, Diego, Baudin-Baillieu, Agnès, Hatin, Isabelle, Chalancon, Guilhem, Glavic, Alvaro, Namy, Olivier, de Crécy-Lagard, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717488/
https://ncbi.nlm.nih.gov/pubmed/26798630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2016.01.473
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