Phosphoinositide 3-kinase-δ regulates fungus-induced allergic lung inflammation through endoplasmic reticulum stress

BACKGROUND: Sensitisation with Aspergillus fumigatus (Af) is known to be associated with severe allergic lung inflammation, but the mechanism remains to be clarified. Phosphoinositide 3-kinase (PI3K)-δ and endoplasmic reticulum (ER) stress are suggested to be involved in steroid-resistant lung infla...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Lee, Kyung Sun, Jeong, Jae Seok, Kim, So Ri, Cho, Seong Ho, Kolliputi, Narasaiah, Ko, Yun Hee, Lee, Kyung Bae, Park, Suk Chul, Park, Hae Jin, Lee, Yong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Respiratory Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717427/
https://ncbi.nlm.nih.gov/pubmed/26543090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207096
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