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Phosphatidylinositol 3‐kinase‐δ controls endoplasmic reticulum membrane fluidity and permeability in fungus‐induced allergic inflammation in mice

BACKGROUND AND PURPOSE: Phosphatidylinositol 3‐kinase (PI3K), especially PI3K‐δ, and endoplasmic reticulum (ER) stress play important roles in refractory asthma induced by the fungus Aspergillus fumigatus through mechanisms that are not well understood. Here we have investigated these mechanisms, us...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Lee, Hwa‐Young, Lee, Geum‐Hwa, Kim, Hyung‐Ryong, Lee, Yong‐Chul, Chae, Han‐Jung
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060358/
https://ncbi.nlm.nih.gov/pubmed/31713846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14917
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