Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners

PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to the classes IA PI3Ks p110α and p110β. However, the immunological role of PI3K-δ isoform is...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Immunol Res
Main Authors: Kim, So Ri, Park, Hae Jin, Lee, Kyung Bae, Kim, Hee Jung, Jeong, Jae Seok, Cho, Seong Ho, Lee, Yong Chul
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997282/
https://ncbi.nlm.nih.gov/pubmed/32009326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2020.12.2.338
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