The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design

OBJECTIVE: Developing a vaccine that is cross-reactive between HCV genotypes requires data on T cell antigenic targets that extends beyond genotype-1. We characterised T cell immune responses against HCV genotype-3, the most common infecting genotype in the UK and Asia, and assessed within genotype...

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Détails bibliographiques
Publié dans:Gut
Auteurs principaux: von Delft, Annette, Humphreys, Isla S, Brown, Anthony, Pfafferott, Katja, Lucas, Michaela, Klenerman, Paul, Lauer, Georg M, Cox, Andrea L, Gaudieri, Silvana, Barnes, Eleanor
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Hepatology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717358/
https://ncbi.nlm.nih.gov/pubmed/26092843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308724
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