Effects of 2‐year calorie restriction on circulating levels of IGF‐1, IGF‐binding proteins and cortisol in nonobese men and women: a randomized clinical trial

Young‐onset calorie restriction (CR) in rodents decreases serum IGF‐1 concentration and increases serum corticosterone levels, which have been hypothesized to play major roles in mediating its anticancer and anti‐aging effects. However, little is known on the effects of CR on the IGF‐1 system and co...

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Publicado en:Aging Cell
Autores principales: Fontana, Luigi, Villareal, Dennis T., Das, Sai K., Smith, Steven R., Meydani, Simin N., Pittas, Anastassios G., Klein, Samuel, Bhapkar, Manjushri, Rochon, James, Ravussin, Eric, Holloszy, John O.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717266/
https://ncbi.nlm.nih.gov/pubmed/26443692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12400
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