Effects of 2‐year calorie restriction on circulating levels of IGF‐1, IGF‐binding proteins and cortisol in nonobese men and women: a randomized clinical trial

Young‐onset calorie restriction (CR) in rodents decreases serum IGF‐1 concentration and increases serum corticosterone levels, which have been hypothesized to play major roles in mediating its anticancer and anti‐aging effects. However, little is known on the effects of CR on the IGF‐1 system and co...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Fontana, Luigi, Villareal, Dennis T., Das, Sai K., Smith, Steven R., Meydani, Simin N., Pittas, Anastassios G., Klein, Samuel, Bhapkar, Manjushri, Rochon, James, Ravussin, Eric, Holloszy, John O.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717266/
https://ncbi.nlm.nih.gov/pubmed/26443692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12400
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