Effects of 2‐year calorie restriction on circulating levels of IGF‐1, IGF‐binding proteins and cortisol in nonobese men and women: a randomized clinical trial

Young‐onset calorie restriction (CR) in rodents decreases serum IGF‐1 concentration and increases serum corticosterone levels, which have been hypothesized to play major roles in mediating its anticancer and anti‐aging effects. However, little is known on the effects of CR on the IGF‐1 system and co...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Fontana, Luigi, Villareal, Dennis T., Das, Sai K., Smith, Steven R., Meydani, Simin N., Pittas, Anastassios G., Klein, Samuel, Bhapkar, Manjushri, Rochon, James, Ravussin, Eric, Holloszy, John O.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717266/
https://ncbi.nlm.nih.gov/pubmed/26443692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12400
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