טוען...

Rational manual and automated scoring thresholds for the immunohistochemical detection of TP53 missense mutations in human breast carcinomas

Missense mutations in TP53 are common in human breast cancer, have been associated with worse prognosis, and may predict therapy effect. TP53 missense mutations are associated with aberrant accumulation of p53 protein in tumor cell nuclei. Previous studies have used relatively arbitrary cutoffs to c...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Appl Immunohistochem Mol Morphol
Main Authors: Taylor, Nicholas J., Nikolaishvili-Feinberg, Nana, Midkiff, Bentley R., Conway, Kathleen, Millikan, Robert C., Geradts, Joseph
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716889/
https://ncbi.nlm.nih.gov/pubmed/26200835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0000000000000207
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