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New Insight into the Anti-liver Fibrosis Effect of Multitargeted Tyrosine Kinase Inhibitors: From Molecular Target to Clinical Trials

Tyrosine kinases (TKs) is a family of tyrosine protein kinases with important functions in the regulation of a broad variety of physiological cell processes. Overactivity of TK disturbs cellular homeostasis and has been linked to the development of certain diseases, including various fibrotic diseas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Qu, Kai, Huang, Zichao, Lin, Ting, Liu, Sinan, Chang, Hulin, Yan, Zhaoyong, Zhang, Hongxin, Liu, Chang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716646/
https://ncbi.nlm.nih.gov/pubmed/26834633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00300
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