Over-activation of TLR5 signaling by high-dose flagellin induces liver injury in mice

Flagellin is a potent activator of a broad range of cell types that are involved in innate and adaptive immunity. Therefore, it is a good adjuvant candidate for vaccines, and it might function as a biological protectant against both major acute radiation syndrome during cancer radiotherapy and a mit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Xiao, Yang, Liu, Fang, Yang, Jingyi, Zhong, Maohua, Zhang, Ejuan, Li, Yaoming, Zhou, Dihan, Cao, Yuan, Li, Wei, Yu, Jie, Yang, Yi, Yan, Huimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716618/
https://ncbi.nlm.nih.gov/pubmed/25418468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2014.110
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