Blast traumatic brain injury induced cognitive deficits are attenuated by pre- or post-injury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4

BACKGROUND: Blast traumatic brain injury (B-TBI) affects military and civilian personnel. Presently there are no approved drugs for blast brain injury. METHODS: Exendin-4, administered subcutaneously, was evaluated as a pre-treatment (48 hours) and post-injury treatment (2 hours) on neurodegeneratio...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Tweedie, David, Rachmany, Lital, Rubovitch, Vardit, Li, Yazhou, Holloway, Harold W., Lehrmann, Elin, Zhang, Yongqing, Becker, Kevin G., Perez, Evelyn, Hoffer, Barry J., Pick, Chaim G., Greig, Nigel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715981/
https://ncbi.nlm.nih.gov/pubmed/26327236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.07.489
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