Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration

Mild blast traumatic brain injury (B-TBI) induced lasting cognitive impairments in novel object recognition and less severe deficits in Y-maze behaviors. B-TBI significantly reduced the levels of synaptophysin (SYP) protein staining in cortical (CTX) and hippocampal (HIPP) tissues. Treatment with ex...

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Publicado no:Sci Rep
Main Authors: Rachmany, Lital, Tweedie, David, Rubovitch, Vardit, Li, Yazhou, Holloway, Harold W., Kim, Dong Seok, Ratliff, Whitney A., Saykally, Jessica N., Citron, Bruce A., Hoffer, Barry J., Greig, Nigel H., Pick, Chaim G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473835/
https://ncbi.nlm.nih.gov/pubmed/28623327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03792-9
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