Cyclin D1 promotes androgen-dependent DNA damage repair in prostate cancer cells

Therapy resistance and poor outcome in prostate cancer is associated with increased expression of Cyclin D1. Androgens promote DNA double strand break repair to reduce DNA damage, and cyclin D1 was also shown to enhance DNA damage repair (DDR). In this study, we investigated the significance of cycl...

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Publicado en:Cancer Res
Autores principales: Casimiro, Mathew C., Di Sante, Gabriele, Ju, Xiaoming, Li, Zhiping, Chen, Ke, Crosariol, Marco, Yaman, Ismail, Gormley, Michael, Meng, Hui, Lisanti, Michael P., Pestell, Richard G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715975/
https://ncbi.nlm.nih.gov/pubmed/26582866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0999
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