TrkB Gene Therapy by Adeno-Associated Virus Enhances Recovery after Cervical Spinal Cord Injury

Unilateral cervical spinal cord hemisection at C2 (C2SH) interrupts descending bulbospinal inputs to phrenic motoneurons, paralyzing the diaphragm muscle. Recovery after C2SH is enhanced by brain derived neurotrophic factor (BDNF) signaling via the tropomyosin-related kinase subtype B (TrkB) recepto...

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Bibliografske podrobnosti
izdano v:Exp Neurol
Main Authors: Martínez-Gálvez, Gabriel, Zambrano, Juan M., Diaz Soto, Juan C., Zhan, Wen-Zhi, Gransee, Heather M., Sieck, Gary C., Mantilla, Carlos B.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715974/
https://ncbi.nlm.nih.gov/pubmed/26607912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.11.007
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