TrkB Gene Therapy by Adeno-Associated Virus Enhances Recovery after Cervical Spinal Cord Injury

Unilateral cervical spinal cord hemisection at C2 (C2SH) interrupts descending bulbospinal inputs to phrenic motoneurons, paralyzing the diaphragm muscle. Recovery after C2SH is enhanced by brain derived neurotrophic factor (BDNF) signaling via the tropomyosin-related kinase subtype B (TrkB) recepto...

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Bibliografiset tiedot
Julkaisussa:Exp Neurol
Päätekijät: Martínez-Gálvez, Gabriel, Zambrano, Juan M., Diaz Soto, Juan C., Zhan, Wen-Zhi, Gransee, Heather M., Sieck, Gary C., Mantilla, Carlos B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715974/
https://ncbi.nlm.nih.gov/pubmed/26607912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.11.007
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