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Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1

In an RNAi library screen for loss of kinetoplast DNA (kDNA), we identified an uncharacterized Trypanosoma brucei protein, named TbLOK1, required for maintenance of mitochondrial shape and function. We found the TbLOK1 protein located in discrete patches in the mitochondrial outer membrane. Knockdow...

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Bibliografski detalji
Izdano u:Mol Microbiol
Glavni autori: Povelones, Megan L., Tiengwe, Calvin, Gluenz, Eva, Gull, Keith, Englund, Paul T., Jensen, Robert E.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715881/
https://ncbi.nlm.nih.gov/pubmed/23336702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12089
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