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A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology
The mitochondrial genome of Trypanosoma brucei, called kinetost DNA (kDNA), is a network of topologically interlocked DNA rings including several thousand minicircles and a few dozen maxicircles. kDNA synthesis involves release of minicircles from the network, replication of the free minicircles, an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993328/ https://ncbi.nlm.nih.gov/pubmed/19019151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06493.x |
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