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A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology

The mitochondrial genome of Trypanosoma brucei, called kinetost DNA (kDNA), is a network of topologically interlocked DNA rings including several thousand minicircles and a few dozen maxicircles. kDNA synthesis involves release of minicircles from the network, replication of the free minicircles, an...

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Main Authors: Lindsay, Megan E., Gluenz, Eva, Gull, Keith, Englund, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993328/
https://ncbi.nlm.nih.gov/pubmed/19019151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06493.x
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