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Depletion of Mitochondrial Acyl Carrier Protein in Bloodstream-Form Trypanosoma brucei Causes a Kinetoplast Segregation Defect

Like other eukaryotes, trypanosomes have an essential type II fatty acid synthase in their mitochondrion. We have investigated the function of this synthase in bloodstream-form parasites by studying the effect of a conditional knockout of acyl carrier protein (ACP), a key player in this fatty acid s...

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Detalhes bibliográficos
Main Authors: Clayton, April M., Guler, Jennifer L., Povelones, Megan L., Gluenz, Eva, Gull, Keith, Smith, Terry K., Jensen, Robert E., Englund, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067480/
https://ncbi.nlm.nih.gov/pubmed/21239625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00290-10
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