Human papillomavirus capsids preferentially bind and infect tumor cells

We previously determined that human papillomavirus (HPV) virus-like particles (VLPs) and pseudovirions (PsV) did not, respectively, bind to or infect intact epithelium of the cervicovaginal tract. However, they strongly bound heparin sulfate proteoglycans (HSPG) on the basement membrane of disrupted...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Kines, Rhonda C., Cerio, Rebecca J., Roberts, Jeffrey N., Thompson, Cynthia D., de Los Pinos, Elisabet, Lowy, Douglas R., Schiller, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715788/
https://ncbi.nlm.nih.gov/pubmed/26317490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29823
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