The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding

Using a murine challenge model, we previously determined that human papillomavirus (HPV) pseudovirions initially bind preferentially to the cervicovaginal basement membrane (BM) at sites of trauma. We now report that the capsids undergo a conformational change while bound to the BM that results in L...

Full description

Saved in:
Bibliographic Details
Main Authors: Kines, Rhonda C., Thompson, Cynthia D., Lowy, Douglas R., Schiller, John T., Day, Patricia M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787115/
https://ncbi.nlm.nih.gov/pubmed/19920181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908502106
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items