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The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding
Using a murine challenge model, we previously determined that human papillomavirus (HPV) pseudovirions initially bind preferentially to the cervicovaginal basement membrane (BM) at sites of trauma. We now report that the capsids undergo a conformational change while bound to the BM that results in L...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787115/ https://ncbi.nlm.nih.gov/pubmed/19920181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908502106 |
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