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Effects of APOE promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly

The polymorphism of the Apolipoprotein E (APOE) promoter rs405509 can regulate the transcriptional activity of the APOE gene and is related to Alzheimer's disease (AD). However, its effects on cognitive performance and the underlying brain mechanisms remain unknown. Here, we performed a battery...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Shu, Ni, Li, Xin, Ma, Chao, Zhang, Junying, Chen, Kewei, Liang, Ying, Chen, Yaojing, Zhang, Zhanjun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715757/
https://ncbi.nlm.nih.gov/pubmed/26314833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.22954
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