Effects of an APOE Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging

Background: The rs405509 polymorphism ofthe apolipoprotein E (APOE) promoter is related to Alzheimer’sdisease (AD). The T/T allele of rs405509 is known to decrease the transcription of the APOE gene and lead to impairments in specific brain structural networks with aging; thus, it is an important ri...

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Udgivet i:Front Aging Neurosci
Main Authors: Zhang, Qirui, Wu, Lingli, Du, Chao, Xu, Kai, Sun, Jinping, Zhang, Junying, Li, He, Li, Xin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338603/
https://ncbi.nlm.nih.gov/pubmed/32694990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00183
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