Precuneus degeneration in nondemented elderly individuals with APOE ɛ4: Evidence from structural and functional MRI analyses

Neurodegenerative diseases such as Alzheimer's disease (AD) have been recognized to exhibit disease‐specific brain vulnerability patterns. Apolipoprotein E (APOE) ɛ4 allele imparts a high genetic risk of developing AD. Whether the APOE ɛ4 allele damages the brain when cognitive functions are st...

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Udgivet i:Hum Brain Mapp
Main Authors: Chen, Yaojing, Liu, Zhen, Zhang, Junying, Chen, Kewei, Yao, Li, Li, Xin, Gong, Gaolang, Wang, Jun, Zhang, Zhanjun
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866889/
https://ncbi.nlm.nih.gov/pubmed/27593520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23359
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