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Precuneus degeneration in nondemented elderly individuals with APOE ɛ4: Evidence from structural and functional MRI analyses

Neurodegenerative diseases such as Alzheimer's disease (AD) have been recognized to exhibit disease‐specific brain vulnerability patterns. Apolipoprotein E (APOE) ɛ4 allele imparts a high genetic risk of developing AD. Whether the APOE ɛ4 allele damages the brain when cognitive functions are st...

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Dettagli Bibliografici
Pubblicato in:Hum Brain Mapp
Autori principali: Chen, Yaojing, Liu, Zhen, Zhang, Junying, Chen, Kewei, Yao, Li, Li, Xin, Gong, Gaolang, Wang, Jun, Zhang, Zhanjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866889/
https://ncbi.nlm.nih.gov/pubmed/27593520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23359
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