Activity and Toxicity of Intravenous Erwinia Asparaginase Following Allergy to E. coli‐Derived Asparaginase in Children and Adolescents With Acute Lymphoblastic Leukemia

BACKGROUND: Erwinia asparaginase is antigenically distinct from E.coli‐derived asparaginase and may be used after E.coli‐derived asparaginase hypersensitivity. In a single‐arm, multicenter study, we evaluated nadir serum asparaginase activity (NSAA) and toxicity with intravenously administered aspar...

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Pubblicato in:Pediatr Blood Cancer
Autori principali: Vrooman, Lynda M., Kirov, Ivan I., Dreyer, ZoAnn E., Kelly, Michael, Hijiya, Nobuko, Brown, Patrick, Drachtman, Richard A., Messinger, Yoav H., Ritchey, A. Kim, Hale, Gregory A., Maloney, Kelly, Lu, Yuan, Plourde, Paul V., Silverman, Lewis B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715717/
https://ncbi.nlm.nih.gov/pubmed/26376459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25757
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