Activity and Toxicity of Intravenous Erwinia Asparaginase Following Allergy to E. coli‐Derived Asparaginase in Children and Adolescents With Acute Lymphoblastic Leukemia

BACKGROUND: Erwinia asparaginase is antigenically distinct from E.coli‐derived asparaginase and may be used after E.coli‐derived asparaginase hypersensitivity. In a single‐arm, multicenter study, we evaluated nadir serum asparaginase activity (NSAA) and toxicity with intravenously administered aspar...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Vrooman, Lynda M., Kirov, Ivan I., Dreyer, ZoAnn E., Kelly, Michael, Hijiya, Nobuko, Brown, Patrick, Drachtman, Richard A., Messinger, Yoav H., Ritchey, A. Kim, Hale, Gregory A., Maloney, Kelly, Lu, Yuan, Plourde, Paul V., Silverman, Lewis B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715717/
https://ncbi.nlm.nih.gov/pubmed/26376459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25757
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