Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

Erwinia asparaginase is an important component in the treatment of pediatric acute lymphoblastic leukemia. A large variability in serum concentrations has been observed after intravenous Erwinia asparaginase. Currently, Dutch Childhood Oncology Group protocols dose alterations are based on trough co...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Sassen, Sebastiaan D.T., Mathôt, Ron A.A., Pieters, Rob, Kloos, Robin Q.H., de Haas, Valérie, Kaspers, Gertjan J.L., van den Bos, Cor, Tissing, Wim J.E., te Loo, Maroeska, Bierings, Marc B., Kollen, Wouter J.W., Zwaan, Christian M., van der Sluis, Inge M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394946/
https://ncbi.nlm.nih.gov/pubmed/28250007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.149195
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