Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

Erwinia asparaginase is an important component in the treatment of pediatric acute lymphoblastic leukemia. A large variability in serum concentrations has been observed after intravenous Erwinia asparaginase. Currently, Dutch Childhood Oncology Group protocols dose alterations are based on trough co...

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Publicat a:Haematologica
Autors principals: Sassen, Sebastiaan D.T., Mathôt, Ron A.A., Pieters, Rob, Kloos, Robin Q.H., de Haas, Valérie, Kaspers, Gertjan J.L., van den Bos, Cor, Tissing, Wim J.E., te Loo, Maroeska, Bierings, Marc B., Kollen, Wouter J.W., Zwaan, Christian M., van der Sluis, Inge M.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394946/
https://ncbi.nlm.nih.gov/pubmed/28250007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.149195
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