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Screening and Identification of Inhibitors of Trypanosoma brucei Cathepsin L with Antitrypanosomal Activity

Current treatment options for human African trypanosomiasis (HAT) are ineffective, and they have several well-known clinical limitations. In our continued efforts to identify chemotypes that can be developed into clinically useful drugs, we screened a targeted compound library against the major cath...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Biol Drug Des
Hauptverfasser: Jefferson, Tierra, McShan, Danielle, Warfield, Jasmine, Ogungbe, Ifedayo Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715686/
https://ncbi.nlm.nih.gov/pubmed/26242248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12628
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