Dual catalytic decarboxylative allylations of α-amino acids and their divergent mechanisms

The room temperature radical decarboxylative allylation of N-protected α-amino acids and esters has been accomplished via a combination of palladium and photoredox catalysis to provide homoallylic amines. Mechanistic investigations revealed that the stability of the α-amino radical, which is formed...

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Bibliographic Details
Published in:Chemistry
Main Authors: Lang, Simon B., O’Nele, Kathryn M., Douglas, Justin T., Tunge, Jon A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715668/
https://ncbi.nlm.nih.gov/pubmed/26526115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201503644
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