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S-Nitrosylation of Bcl-2 Negatively Affects Autophagy in Lung Epithelial Cells

Autophagy is a catabolic cellular mechanism involving lysosomal degradation of unwanted cellular components. Interaction between Beclin-1 and Bcl-2 proteins is known to play a critical role in the initiation of autophagy. We report that malignantly transformed lung epithelial cells are resistant to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biochem
Prif Awduron: Wright, Clayton, Iyer, Anand Krishnan V., Kulkarni, Yogesh, Azad, Neelam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715592/
https://ncbi.nlm.nih.gov/pubmed/26241894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25303
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