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A conserved structural motif mediates retrograde trafficking of Shiga toxin types 1 and 2
Shiga toxin-producing E. coli (STEC) produce two types of Shiga toxin (STx): STx1 and STx2. The toxin A-subunits block protein synthesis while the B-subunits mediate retrograde trafficking. STEC infections do not have definitive treatments, and there is growing interest in generating toxin transport...
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| Udgivet i: | Traffic |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715488/ https://ncbi.nlm.nih.gov/pubmed/26420131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12338 |
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