Integrative Molecular Profiling Reveals Asparagine Synthetase Is a Target in Castration-Resistant Prostate Cancer

The identification of new and effective therapeutic targets for the lethal, castration-resistant stage of prostate cancer (CRPC) has been challenging because of both the paucity of adequate frozen tissues and a lack of integrated molecular analysis. Therefore, in this study, we performed a genome-wi...

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Vydáno v:Am J Pathol
Hlavní autoři: Sircar, Kanishka, Huang, Heng, Hu, Limei, Cogdell, David, Dhillon, Jasreman, Tzelepi, Vassiliki, Efstathiou, Eleni, Koumakpayi, Ismaël H., Saad, Fred, Luo, Dijun, Bismar, Tarek A., Aparicio, Ana, Troncoso, Patricia, Navone, Nora, Zhang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715215/
https://ncbi.nlm.nih.gov/pubmed/22245216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.11.030
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