Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone

PURPOSE: Persistent androgen signaling is implicated in castrate-resistant prostate cancer (CRPC) progression. This study aimed to evaluate androgen signaling in bone marrow–infiltrating cancer and testosterone in blood and bone marrow and to correlate with clinical observations. PATIENTS AND METHOD...

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Detalhes bibliográficos
Main Authors: Efstathiou, Eleni, Titus, Mark, Tsavachidou, Dimitra, Tzelepi, Vassiliki, Wen, Sijin, Hoang, Anh, Molina, Arturo, Chieffo, Nicole, Smith, Lisa A., Karlou, Maria, Troncoso, Patricia, Logothetis, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295561/
https://ncbi.nlm.nih.gov/pubmed/22184395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.7675
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