Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone

PURPOSE: Persistent androgen signaling is implicated in castrate-resistant prostate cancer (CRPC) progression. This study aimed to evaluate androgen signaling in bone marrow–infiltrating cancer and testosterone in blood and bone marrow and to correlate with clinical observations. PATIENTS AND METHOD...

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Autors principals: Efstathiou, Eleni, Titus, Mark, Tsavachidou, Dimitra, Tzelepi, Vassiliki, Wen, Sijin, Hoang, Anh, Molina, Arturo, Chieffo, Nicole, Smith, Lisa A., Karlou, Maria, Troncoso, Patricia, Logothetis, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2012
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295561/
https://ncbi.nlm.nih.gov/pubmed/22184395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.7675
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