Mitosis Phase Enrichment with Identification of Mitotic Centromere-Associated Kinesin As a Therapeutic Target in Castration-Resistant Prostate Cancer

The recently described transcriptomic switch to a mitosis program in castration-resistant prostate cancer (CRPC) suggests that mitotic proteins may be rationally targeted at this lethal stage of the disease. In this study, we showed upregulation of the mitosis-phase at the protein level in our cohor...

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Main Authors: Sircar, Kanishka, Huang, Heng, Hu, Limei, Liu, Yuexin, Dhillon, Jasreman, Cogdell, David, Aprikian, Armen, Efstathiou, Eleni, Navone, Nora, Troncoso, Patricia, Zhang, Wei
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281954/
https://ncbi.nlm.nih.gov/pubmed/22363599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031259
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