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Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis

Proper bi-orientation of chromosomes is critical for the accurate segregation of chromosomes in mitosis. A key regulator of this process is MCAK, the mitotic centromere-associated kinesin. During mitosis the activity and localization of MCAK are regulated by mitotic key kinases including Plk1 and Au...

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Detalhes bibliográficos
Main Authors: Sanhaji, Mourad, Ritter, Andreas, Belsham, Hannah R., Friel, Claire T., Roth, Susanne, Louwen, Frank, Yuan, Juping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102797/
https://ncbi.nlm.nih.gov/pubmed/24931513
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