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Localized hypoxia within the subgranular zone determines the early survival of newborn hippocampal granule cells
The majority of adult hippocampal newborn cells die during early differentiation from intermediate progenitors (IPCs) to immature neurons. Neural stem cells in vivo are located in a relative hypoxic environment, and hypoxia enhances their survival, proliferation and stemness in vitro. Thus, we hypot...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714973/ https://ncbi.nlm.nih.gov/pubmed/26476335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08722 |
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