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Localized hypoxia within the subgranular zone determines the early survival of newborn hippocampal granule cells

The majority of adult hippocampal newborn cells die during early differentiation from intermediate progenitors (IPCs) to immature neurons. Neural stem cells in vivo are located in a relative hypoxic environment, and hypoxia enhances their survival, proliferation and stemness in vitro. Thus, we hypot...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Chatzi, Christina, Schnell, Eric, Westbrook, Gary L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714973/
https://ncbi.nlm.nih.gov/pubmed/26476335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08722
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