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Localized hypoxia within the subgranular zone determines the early survival of newborn hippocampal granule cells

The majority of adult hippocampal newborn cells die during early differentiation from intermediate progenitors (IPCs) to immature neurons. Neural stem cells in vivo are located in a relative hypoxic environment, and hypoxia enhances their survival, proliferation and stemness in vitro. Thus, we hypot...

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Опубликовано в: :eLife
Главные авторы: Chatzi, Christina, Schnell, Eric, Westbrook, Gary L
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714973/
https://ncbi.nlm.nih.gov/pubmed/26476335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08722
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