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Hijacking leucyl-tRNA synthetase to amino acid-dependent regulation of TORC1
TORC1 activity in all eukaryotes is dependent on amino acids availability. However, the mechanism through which TORC1 senses amino acids is still a mystery unfolding like a detective story. Two new studies, implicate leucyl-tRNA synthetase in this evolving story.
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714921/ https://ncbi.nlm.nih.gov/pubmed/22500735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.03.028 |
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