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Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis

Enhancers are the primary determinants of cell identity, but the regulatory components controlling enhancer turnover during lineage commitment remain largely unknown. Here we compare the enhancer landscape, transcriptional factor occupancy and transcriptomic changes in human fetal and adult hematopo...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Huang, Jialiang, Liu, Xin, Li, Dan, Shao, Zhen, Cao, Hui, Zhang, Yuannyu, Trompouki, Eirini, Bowman, Teresa V., Zon, Leonard I., Yuan, Guo-Cheng, Orkin, Stuart H., Xu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714361/
https://ncbi.nlm.nih.gov/pubmed/26766440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.12.014
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