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Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

Establishment and maintenance of the blood system relies on self-renewing hematopoietic stem cells (HSCs) that normally reside in small numbers in the bone marrow niche of adult mammals. This Review describes the developmental origins of HSCs and the molecular mechanisms that regulate lineage-specif...

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Bibliografiske detaljer
Main Authors: Orkin, Stuart H., Zon, Leonard I.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628169/
https://ncbi.nlm.nih.gov/pubmed/18295580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.025
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