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RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

Two cell type-specific Rab proteins, Rab32 and Rab38 (Rab32/38), have been proposed as regulating the trafficking of melanogenic enzymes, including tyrosinase and tyrosinase-related protein 1 (Tyrp1), to melanosomes in melanocytes. Like other GTPases, Rab32/38 function as switch molecules that cycle...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Marubashi, Soujiro, Shimada, Hikaru, Fukuda, Mitsunori, Ohbayashi, Norihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714225/
https://ncbi.nlm.nih.gov/pubmed/26620560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684043
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