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Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes

Amutation in the small GTPase Rab38 gives rise to the mouse coat color phenotype “chocolate” (cht), implicating Rab38 in the regulation of melanogenesis. However, its role remains poorly characterized. We report that cht Rab38(G19V) is inactive and that the nearly normal pigmentation in cht melanocy...

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Detalhes bibliográficos
Main Authors: Wasmeier, Christina, Romao, Maryse, Plowright, Lynn, Bennett, Dorothy C., Raposo, Graça, Seabra, Miguel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064568/
https://ncbi.nlm.nih.gov/pubmed/17043139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606050
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