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Melanosome Maturation Defect in Rab38-deficient Retinal Pigment Epithelium Results in Instability of Immature Melanosomes during Transient Melanogenesis

Pathways of melanosome biogenesis in retinal pigment epithelial (RPE) cells have received less attention than those of skin melanocytes. Although the bulk of melanin synthesis in RPE cells occurs embryonically, it is not clear whether adult RPE cells continue to produce melanosomes. Here, we show th...

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Hlavní autoři: Lopes, Vanda S., Wasmeier, Christina, Seabra, Miguel C., Futter, Clare E.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995718/
https://ncbi.nlm.nih.gov/pubmed/17671165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0268
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